Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1987-03-04
1991-06-11
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
530303, 530851, 530853, 514 12, C07K 0710
Patent
active
050233211
ABSTRACT:
Genes and DNA transfer vectors for the expression of human preprorelaxin; sub-units thereof, including genes and transfer vectors for expression of human prorelaxin and the individual A, B and C peptide chains thereof; and equivalents of all such genes. Methods for synthesis of the peptides involving recombinant DNA techniques.
REFERENCES:
patent: 4267101 (1981-05-01), Bagazzi
patent: 4624804 (1986-11-01), Voelter et al.
patent: 4656249 (1987-04-01), Tregear et al.
Hudson et al. "Molecular Cloning and Characterization of cDNA Sequences Coding for Rat Relaxin" Nature vol. 291, pp. 127-131, 14 May 1981.
Fields, P. A. "Purification and Immunohistochemical Localization of Relaxin . . . " J. of Clinical Endocrinology & Metabolism 52(1)79-85(1981).
Haley, J. et al. "Porcine Relaxin . . . " DNA vol. 1(2) Mar. 1982 pp. 155-162.
Chem. Abstracts 97:727496 (8/30/82).
Hudson Peter J.
Niall High D.
Tregear Geoffrey W.
Howard Florey Institute of Experimental Physiology & Medicine
Moskowitz Margaret
Ossanna Nina
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