Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2003-01-28
2010-10-05
Nguyen, Quang (Department: 1633)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S023100, C536S024300, C435S320100
Reexamination Certificate
active
07807809
ABSTRACT:
Methods for determining whether a tissue sample or an analogue and/or derivative thereof comprises a cell with a chromosome (11:18) translocation associated with malignancies such as mucosa-associated lymphoid tissue (MALT) lymphomas. The invention further provides insight into a novel mechanism of transformation of primary cells. The mechanism involves expression of a fusion proteinaceous molecule comprising at least apoptosis inhibitor 2 (API2) or a functional part, derivative and/or analogue thereof fused to at least one other proteinaceous molecule. The invention also provides a novel nucleic acid sequence and proteinaceous molecule expressed from the sequence termed “MALT-lymphoma associated Translocation (MLT) protein.”
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Baens Mathijs
Dierlamm Judith
Marijnen Peter
Nguyen Quang
TraskBritt
Vlaams Interuniversitair Instituut voor Biotechnologie VZW
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