Moistureless oral drug delivery formulation and method for prepa

Details Moistureless oral drug delivery formulation and method for prepa Moistureless oral drug delivery formulation and method for prepa

1987-05-21

1989-09-19

Schofer, Joseph L.

Drug, bio-affecting and body treating compositions

Lymphokine

424435, A61K 3178, C09K 300

Patent

active

048679704

ABSTRACT:
Oral drug delivery systems are provided formed of compositions which include one or more hydrocolloids solids, such as gelatin, pectin, and sodium carboxymethyl cellulose, and preferably mixtures thereof, which solids contain less than about 5% by weight moisture and preferably comprise less than about 50% by weight of the total formulation; and an ointment base such as mineral oil containing dispersed polyethylene (Plastibase). Such oral drug delivery compositions may be used to deliver to the oral mucosa active ingredients such as steroids, anti-fungal agents, anti-bacterial agents and the like and do not harden even upon prolonged storage or upon filling into containers.

REFERENCES:
patent: 3029187 (1962-04-01), Steinhardt et al.
patent: 3029188 (1962-04-01), Cyr et al.
patent: 3312594 (1967-04-01), Cyr et al.
patent: 3984571 (1976-10-01), Chen
patent: 4540602 (1985-09-01), Motoyama et al.
patent: 4542020 (1985-09-01), Jackson et al.

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