Module for optical detection in microscale fluidic analyses

Details Module for optical detection in microscale fluidic analyses Module for optical detection in microscale fluidic analyses

1995-04-20

1998-05-26

McGraw, Vincent P.

Optics: measuring and testing

Sample, specimen, or standard holder or support

Fluid containers

356410, 356440, G01N 2103, G01N 2105

Patent

active

057574820

ABSTRACT:
Disclosed is an apparatus for fluidic separation systems comprising a microfabricated conduit including a usefully long optical pathlength. The provision of a usefully long optical pathlength in the apparatus greatly improves the sensitivity of detection of separated analytes without compromising the resolving power of the apparatus.

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Sobek et al "A Microfabricated Flow Chamber for Optical Measurements in Fluids". Proceedings of IEEE Micro Electro Mechanical Systems, Fort Lauderdale, Fl, Feb. 7, 1993, pp. 219-224.
Mesaros et al., "Continuous Electrophoretic Separations in Narrow Channels Coupled to Small-Bore Capillaries", Anal. Chem., 65:3313-3319 (1993).

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