Modulators that promote cell surface expression of odorant...

Details Modulators that promote cell surface expression of odorant... Modulators that promote cell surface expression of odorant...

2008-09-16

2008-09-16

Ulm, John D (Department: 1649)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S007210, C435S069100, C435S361000

Reexamination Certificate

active

11156516

ABSTRACT:
The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for odorant receptor accessory protein polymorphisms and mutations associated with disease states, as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins.

REFERENCES:
patent: 2005/0233418 (2005-10-01), Baum et al.

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