Modulators of the glucocorticoid receptor and method

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S195000, C548S160000, C548S222000, C548S233000, C548S332500, C546S139000, C546S152000, C546S270700, C546S285000, C514S367000, C514S377000, C514S394000, C514S398000

Reexamination Certificate

active

06995181

ABSTRACT:
Novel non-steroidal compounds are provided which are glucocorticoid receptor modulators which are useful in treating diseases requiring glucocorticoid receptor agonist or antagonist therapy such as obesity, diabetes, inflammatory and immune disorders, and have the structurewhere Z is CONR1R2or CH2NR1R2and where R, Ra, Rb, Rc, Rd, Z, A and B are defined herein.

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