Modulators of the function of receptors of the TNF/NGF...

Details Modulators of the function of receptors of the TNF/NGF... Modulators of the function of receptors of the TNF/NGF...

2006-08-01

2006-08-01

Chan, Christina (Department: 1644)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

C530S350000

Reexamination Certificate

active

07083788

ABSTRACT:
Proteins which are capable of modulating/mediating the function of RIP, their preparation and uses are provided.

REFERENCES:
patent: 5871726 (1999-02-01), Henderson et al.
patent: 6232081 (2001-05-01), Harper et al.
patent: 96 25941 (1996-08-01), None
Lin et al, Molecular and Cellular Biology 18(10): 5899-5907, Oct. 1998.
Kim et al, Oncogene 19(39): 4491-9, Sep. 2000.
Skolnick et al, From genes to protein structure and function: novel applications of computational approaches in the genomic era, Jan. 2000, TIBTECH 18: 34-39.
Whisstock et al, Quarterly Reviews of Biophysics 36: 307-340, 2003.
Ito et al, Proc Natl Acad Sci 98(8): 4569-4574, Apr. 2001.
Stanger et al., “RIP: A Novel Protein Containing a Death Domain That Interacts with Fas/APO-1 (CD95) in Yeast and Causes Cell Death”,Cell, vol. 81, pp. 513-523, (1995).
Chinnaiyan et al., “FADD, a Novel Death Domain-Containing Protein, Interacts with the Death Domain of Fas and Initiated Apoptosis”,Cell, vol. 81, pp. 505-512, (1995).
Hsu et al., “The TNF Receptor 1-Associated Protein TRADD Signals Cell Death and NF-κB Activation”,Cell, vol. 81, pp. 495-504, (1995).
Malinin et al., “MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and N-1”,Nature, vol. 385, pp. 540-544, (1997).
Duan et al., “RAIDD is a new ‘death’ adaptor molecule”,NATURE, vol. 385, pp. 86-89, (1997).
Ahmad et al., “CRADD, a Novel Human Apoptotic Adaptor Molecule for Caspase-2, and FasL/Tumor Necrosis Factor Receptor-interacting Protein RIP”,Cancer Research, vol. 57, pp. 615-619, (1997).
Verma et al.,Nature, 389:239-242, especially p. 239.
Anderson et al.,Nature, 392:25-30, especially pp. 25 and 30.
Adams et al.,Nature, 377(6547 Suppl):3-174, See enclosed sequence alignment.
Itoh et al.,Cell, 233-243, See abstract; p. 236, column 1, first full paragraph, lines 3-15, and Fi. 3; p. 241, column 1, second full paragraph, lines 8-12.
Ngo et al.,The Protein Folding Problem and Tertiary Structure Prediction, Merz et al(ed.), Birkhauser, Boston, MA pp. 492-495 (1994).

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