Modulators of the function of FAS/AP01 receptors

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S252300, C435S254110, C435S320100, C435S325000, C530S350000, C536S023500, C514S012200

Reexamination Certificate

active

07108999

ABSTRACT:
Proteins capable of modulating the function of FAS/APO1 are provided. The proteins may be prepared by culturing a host cell transformed with a vector containing the DNA encoding such a protein under suitable conditions and isolating the protein.

REFERENCES:
patent: WO 93/09218 (1993-05-01), None
patent: WO96/12735 (1996-05-01), None
patent: WO96/30404 (1996-10-01), None
patent: WO96/31603 (1996-10-01), None
patent: WO96/36730 (1996-11-01), None
Marshall E. Gene therapy's growing pains. Science. Aug. 25, 1995;269(5227):1050-5.
Blau et al. Gene therapy—a novel form of drug delivery. N Engl J Med. Nov. 2, 1995;333(18):1204-7.
Branch AD. A good antisense molecule is hard to find. Trends Biochem Sci. Feb. 1998;23(2):45-50.
Jen et al. Supression of gene expression by targeted disruption of messenger RNA: available options and current strategies. Stem Cells. 2000;18(5):307-19.
Clement et al, “Fas and Tumor Necrosis Factor Receptor mediated Cell Death: Similarities and Distinctions”,J. Exp. Med., vol. 180, pp. 557-567, Aug. 1994.
Song et al, “Aggregation of the Intracellular Domain of the Type 1 Tumor Necrosis Factor Receptor Defined by the Two-hybrid System”,The J. of Biol. Chemistry, vol. 269(36), pp. 22492-22495, 1994.
Itoh et al, “A novel protein domain required for apoptosis”,Journal of Biological Chemistry, vol. 268, No. 15, pps. 10932-10937 (May 25, 1993).
Nagata et al, “Fas and Fas ligand: A death factor and its receptor”,Advances in Immunology, vol. 57, pp. 129-144 (Jan. 1, 1994).
GenBank Accession No. Q15121, “Astrocytic phosphoprotein”, Nov. 1, 1997.
GenBank Accession No. X86809, “H. sapiensmRNA for major astrocytic phosphoprotein PEA-15”, Jul. 23, 1996.
GenBank Accession No. P25445, “FASL Receptor precursor (apoptosis-mediating surface antigen FAS) (APO-1 Antigen) (CD95 Antigen)”; May 1, 1992.
GenBank Accession No. P16157, “Ankyrin 1 (Erythrocyte Ankyrin)”; Apr. 1, 1990.
GenBank Accession No. P08138, “Low-affinity nerve growth factor receptor precursor (NGF receptor)”, Aug. 1, 1988.
GenBank Accession No. P19438, “Tumor necrosis factor recptor 1 precursor (Tumor necrosis factor binding protein 1)”, Feb. 1, 1991.
GenBank Accession No. NP—002459; “Myeloid differentiation primary response gene (88)”, Mar. 19, 1999.
GenBank Accession No. P22366; “Myeloid differentiation primary response protein MYD88”; Aug. 1, 1991.
GenBank Accession No. P53355; “Death-associated protein kinase 1 (DAP kinase 1)”, Oct. 1, 1996.
Baker et al., “Transducers of life and death:TNF receptor superfamily and associated proteins.”, ONCOGENE, vol. 12, No. 1, pps. 1-9 (Jan. 4, 1996).
Boldin et al., “A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain.”, Journal of Biological Chemistry, vol. 270, No. 14, pp. 7795-7798 (1995).
Chinnaiyan et al., “FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.”, CELL, vol. 81, pp. 505-512 (May 19, 1995).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Modulators of the function of FAS/AP01 receptors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Modulators of the function of FAS/AP01 receptors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modulators of the function of FAS/AP01 receptors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3562677

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.