Modulators of muscarinic receptors

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

07858790

ABSTRACT:
The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

REFERENCES:
patent: 3654287 (1972-04-01), Dykstra
patent: 3666764 (1972-05-01), Campbell et al.
patent: 3959475 (1976-05-01), Bauer et al.
patent: 3962259 (1976-06-01), Bauer et al.
patent: 4233307 (1980-11-01), Ono et al.
patent: 4349549 (1982-09-01), Roszkowski et al.
patent: 4558049 (1985-12-01), Bernardi et al.
patent: 5091387 (1992-02-01), Evans et al.
patent: 5219860 (1993-06-01), Chambers et al.
patent: 5536716 (1996-07-01), Chen et al.
patent: 5576321 (1996-11-01), Krushinski, Jr. et al.
patent: 5578593 (1996-11-01), Chen et al.
patent: 5614523 (1997-03-01), Audia et al.
patent: 5627196 (1997-05-01), Audia et al.
patent: 5652235 (1997-07-01), Chen et al.
patent: 5658921 (1997-08-01), Perregaard et al.
patent: 5741789 (1998-04-01), Hibschman et al.
patent: 5789402 (1998-08-01), Audia et al.
patent: 5817679 (1998-10-01), Shen et al.
patent: 5885999 (1999-03-01), Elliott et al.
patent: 6013652 (2000-01-01), Maccoss et al.
patent: 6130217 (2000-10-01), Arnold et al.
patent: 6166040 (2000-12-01), Fairhurst et al.
patent: 6326372 (2001-12-01), Evans et al.
patent: 6326375 (2001-12-01), Fukami et al.
patent: 6436962 (2002-08-01), Hoffman et al.
patent: 6566367 (2003-05-01), Bakthavatchalam et al.
patent: 6720324 (2004-04-01), Marzabadi et al.
patent: 6828440 (2004-12-01), Goehring et al.
patent: 6869960 (2005-03-01), Ito et al.
patent: 6943199 (2005-09-01), De Lombaert et al.
patent: 7045527 (2006-05-01), Chen et al.
patent: 7205417 (2007-04-01), Fukami et al.
patent: 2002/0188124 (2002-12-01), Fukami et al.
patent: 2003/0036652 (2003-02-01), Bakthavatchalam et al.
patent: 2003/0158219 (2003-08-01), Ito et al.
patent: 2004/0054177 (2004-03-01), Otake et al.
patent: 2004/0072847 (2004-04-01), Bakthavatchalam et al.
patent: 2004/0122074 (2004-06-01), Dow et al.
patent: 2004/0142956 (2004-07-01), Chen et al.
patent: 2004/0204397 (2004-10-01), Chaturvedula et al.
patent: 2005/0033048 (2005-02-01), Bakthavatchalam et al.
patent: 2005/0153998 (2005-07-01), Ito et al.
patent: 2005/0176703 (2005-08-01), Gabriel et al.
patent: 2005/0215576 (2005-09-01), Degnan et al.
patent: 2005/0250814 (2005-11-01), Zhou et al.
patent: 2005/0261332 (2005-11-01), Distefano et al.
patent: 2006/0040964 (2006-02-01), Bakthavatchalam et al.
patent: 2006/0058778 (2006-03-01), Arcusa Villacampa et al.
patent: 2006/0111380 (2006-05-01), Otake et al.
patent: 2006/0173027 (2006-08-01), Marzabadi et al.
patent: 2006/0183904 (2006-08-01), Guo et al.
patent: 2006/0211722 (2006-09-01), Jiao et al.
patent: 2006/0217372 (2006-09-01), Blanco-Pillado et al.
patent: 2007/0254903 (2007-11-01), Boatman et al.
patent: 1535967 (2004-10-01), None
patent: 2444728 (1975-04-01), None
patent: 3342164 (1983-11-01), None
patent: 3433327 (1985-03-01), None
patent: 0065864 (1982-12-01), None
patent: 0070171 (1983-01-01), None
patent: 0128886 (1984-12-01), None
patent: 0414289 (1991-02-01), None
patent: 0 445 974 (1991-09-01), None
patent: 0444945 (1991-09-01), None
patent: 0486280 (1992-05-01), None
patent: 0518805 (1992-12-01), None
patent: 0533243 (1993-03-01), None
patent: 0615977 (1994-09-01), None
patent: 0722941 (1996-07-01), None
patent: 1 415 986 (2004-05-01), None
patent: 1575800 (1980-10-01), None
patent: 2131021 (1983-11-01), None
patent: 2308064 (1997-06-01), None
patent: 2355264 (2000-09-01), None
patent: 2355456 (2000-09-01), None
patent: 59059685 (1984-04-01), None
patent: 2001/278886 (2001-10-01), None
patent: 2002/316987 (2002-10-01), None
patent: WO 94/19367 (1994-09-01), None
patent: WO 94/22846 (1994-10-01), None
patent: WO 95/09631 (1995-04-01), None
patent: WO 9511029 (1995-04-01), None
patent: WO 95/14025 (1995-05-01), None
patent: WO 9528389 (1995-10-01), None
patent: WO 9741878 (1997-11-01), None
patent: WO 9741879 (1997-11-01), None
patent: WO 9906434 (1999-02-01), None
patent: WO 9932489 (1999-07-01), None
patent: WO 99/64002 (1999-12-01), None
patent: WO 0006146 (2000-02-01), None
patent: WO0006153 (2000-02-01), None
patent: WO 0006545 (2000-02-01), None
patent: WO 0038720 (2000-07-01), None
patent: WO 01/02386 (2001-01-01), None
patent: WO-01-22919 (2001-04-01), None
patent: WO 01/29027 (2001-04-01), None
patent: WO 0122919 (2001-04-01), None
patent: WO 0145707 (2001-06-01), None
patent: WO 0164213 (2001-09-01), None
patent: WO 02/48152 (2002-06-01), None
patent: WO 02/070511 (2002-09-01), None
patent: WO 02/085354 (2002-10-01), None
patent: WO 02094825 (2002-11-01), None
patent: WO02094825 (2002-11-01), None
patent: WO 03/014083 (2003-02-01), None
patent: WO 03/037271 (2003-05-01), None
patent: WO 03/064425 (2003-08-01), None
patent: WO 03/095427 (2003-11-01), None
patent: WO 03/104236 (2003-12-01), None
patent: WO 03106457 (2003-12-01), None
patent: WO 2004004714 (2004-01-01), None
patent: WO2004010942 (2004-02-01), None
patent: WO2004010943 (2004-02-01), None
patent: WO2004011427 (2004-02-01), None
patent: WO 2004/028459 (2004-04-01), None
patent: WO 2004/050652 (2004-06-01), None
patent: WO 2004/074273 (2004-09-01), None
patent: WO 2004/089307 (2004-10-01), None
patent: WO 2005/016913 (2005-02-01), None
patent: WO 2005/063254 (2005-07-01), None
patent: WO 2005 063745 (2005-07-01), None
patent: WO 2005/065779 (2005-07-01), None
patent: WO 2005/075484 (2005-08-01), None
patent: WO 2005/100360 (2005-10-01), None
patent: WO-2006-001958 (2006-01-01), None
patent: WO 2006/023852 (2006-03-01), None
patent: WO 2006/028239 (2006-03-01), None
patent: WO 2006/058303 (2006-06-01), None
patent: WO 2007/077122 (2007-07-01), None
Bymaster et al Drug Development Research 1997, 40, 158-170.
Custers, Franciscus G. J., et al., Vesamicol and some of its derivatives: Questionalbe ligands for selectively labeling acetylcholine transporters in rat brain,European Journal of Pharmacology, 338 (1997) 177-183.
De Laszlo, S.E., et al., A Nonpeptidic Agonist Ligand of the Human C5A Receptor: Synthesis, Binding Affinity Optimization and Functional Characterization,Bioorganic&Medicinal Chemistry Letters, vol. 7, No. 2, pp. 213-218, 1997.
Efange, S. M. N., et al., (+)-p-([18F]Fluorobenzyl) Spirotrozamicol {(+)-[18F]Spiro-FBT}: Synthesis and Biological Evaluation of a High-Affinity Ligand for the Vesicular Acetylcholine Transporter (VAChT),Nuclear Medicine&Biology, vol. 26. 26, pp. 189-192, 1999.
Malstrom, Rickard E., et al., Pharmacology of H 394/84, a dihydropyridine neuropeptide Y Y1receptor antagonist, in vivo,European Journal of Pharmacology418 (2001) 95-104.
Morrow, Duane F., et al., Synthesis of Some New 17-Spiro-Substituted Steroids,Journal of Medicinal Chemistry, vol. 10, No. 2, Feb. 27, 1967.
Nargund, Ravi P., et al., Peptidomimetic Growth Hormone Secretagogues: Synthesis and Biological Activities of Analogs Varied at the Indole Nucleus of the Prototypical Spiropiperidine L-162,752,Bioorganic&Medicinal Chemistry Letters, vol. 6, No. 14, pp. 1731-1736, 1996.
Nargund, Ravi P., et al., Synthesis and Biological Activities of Camphor-Based Non-Peptide Growth Hormone Secretagogues,Bioorganic&Medicinal Chemistry Letters, vol. 6, No. 11, pp. 1265-1270, 1996.
Oprea, Tudor I., et al., Is There a Difference between Leads and Drugs? A Historical Perspective,J. Chem. Inf. Comput. Sci, 2001, 41. 1308-1315.
Pasternak, Alexander, et al., Potent, Orally Bioavailable Somatostatin Agonists: Good Absorption Achieved by Urea Backbone Cyclization,Bioorganic&Medicinal Chemistry Letters9 (1999) 491-496.
Patchett, A. A., et al., The Synthesis of 17β-Amino-17α-(2′-carboxyethyl)androstane Lactams, Research Laboratories of Merck & Co., In., Rahway, New Jersey, Nov. 1962, vol. 27, pp. 3822-3828.
Pettibone, D. J., et al., Identification of an Orally Active, Nonpeptidyl Oxytocin Antagonist,The Journal of Pharmacology and Experimental Therapeutics, vol. 264, No. 1, 1993, pp. 308-314.
Takemoto, Toshiyasu, et at., Asymmetric synthesis of enantiomerically pure spiro[((2S)-hydroxy)indane-1,4

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Modulators of muscarinic receptors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Modulators of muscarinic receptors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modulators of muscarinic receptors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4208076

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.