Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-04-16
2000-03-28
Kight, John
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514517, 514532, 514534, 514535, 514539, 544363, 544382, 544392, 560 8, 560 11, 560 12, 560 19, 560 27, 560 48, 560 55, 560 57, 560 59, 560101, 560102, 562433, 562441, 562491, A01N 4354, A01N 3710, C07C 6976, C07C22900
Patent
active
060432470
ABSTRACT:
The present invention relates to novel substituted acrylic acids, to methods for their preparation, compositions containing them, and their use for treatment of human and animal disorders, to their use for purification of proteins or glycoproteins, and to their use in diagnosis. The invention also relates to modulation of the activity of molecules with phospho-tyrosine recognition units, including protein tyrosine phosphatases (PTPases) and proteins with Src-homology-2 domains, in in vitro systems, microorganisms, eukaryotic cells, whole animals and human beings.
REFERENCES:
patent: 5770620 (1998-06-01), Mijalli et al.
Williamson et al, Chem. Abstract vol. 78 No. 97492, "Heterocyclic Antiinflammatory Agents", 1972.
El-Batouti, Chem. Abstract vol. 123 No. 293698, "Cinnamic acid der. as inhibitors for dissolution of copper in phosphoric acid." 1995.
Lohaus et al, Chem. abstract, vol. 66 No. 75634. "Friedel-Crafts react. of .beta. dialkylacrylic acid esters."1967.
Blank, et al., Journal of Medicinal Chemistry, vol. 22, No. 7, pp. 840-844, (1979).
Sugihara et al., Arzneim.-Forsch (Drug Res.), vol. 24, No. 10, pp. 1560-1563 (1974).
Cao et al., Bioorganic & Medicinal Chemistry Letters, vol. 5, No. 24, pp. 2953-2958 (1995).
Moran et al., J. Am. Chem. Soc., vol. 117, pp. 10787-10788 (1995).
Andersen Henrik Sune
M.o slashed.ller Niels Peter Hundahl
Madsen Peter
Covington Raymond
Kight John
Lambiris, Esq. Elias
Novo Nordisk A S
Zelson Esq. Steve T.
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