Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-10-17
2006-10-17
Murphy, Joseph (Department: 1646)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S320100, C435S325000, C435S069100
Reexamination Certificate
active
07122332
ABSTRACT:
The present invention provides compositions and methods for modulating leukocyte activation. Nucleic acids encoding proteins and proteins so encoded which are capable of modulating leukocyte activation are provided. Compositions and methods for the treatment of disorders related to leukocyte dysfunction or dysregulation are also provided. Prophylactics and methods for the prevention of such disorders are also provided. Also provided are compositions and methods for diagnostic and prognostic determination of such disorders. Further provided are assays for the identification of bioactive agents capable of modulating leukocyte activation.
REFERENCES:
patent: 5391490 (1995-02-01), Varshavsky et al.
patent: 5494818 (1996-02-01), Baker et al.
patent: WO 00/79267 (2000-12-01), None
patent: WO 0078934 (2000-12-01), None
Baek et al., “Molecular Cloning of a Novel Ubiquitin-specific Protease, UBP41, with Isopeptidase Activity in Chick Skeletal Muscle”,The Journal of Biological Chemistry272:41: 25560-25565 (1997).
Gong et al., “Differential Regulation of Sentrinized Proteins by a Novel Sentrin-specific Protease”,The Journal of Biological Chemistry275:5: 3355-3359 (2000).
Gong et al., “Identification of a Novel Isopeptidase with Dual Specificity for Ubiquitin- and NEDD8-conjugated Proteins”,The Journal of Biological Chemistry275:19: 14212-14216 (2000).
Fu Chong Alan
Mancebo Helena
Wong Brian
Zhou Xiulan X. Z.
Murphy Joseph
Rigel Pharmaceuticals Inc.
Townsend and Townsend / and Crew LLP
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