Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1992-07-14
1995-01-10
Springer, David B.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
548496, C07D20920
Patent
active
053808720
ABSTRACT:
CCK modulators, e.g. agonists or antagonists, of the following formula (I): ##STR1## or a base-addtion salt thereof.
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Jensen, et al. Biochem. Biophys. Acta. 1983, 757, 250-258 "COOH-Terminal Fragments of Cholecystokinin-A New Class of Cholecystokinin Receptor Antagonists".
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Shiosake, et al. J. Med. Chem. 1990, 33, 2950-2952 "Development of CCK-Tetrapeptide Analogues as Potent and Selective CCK-A Receptor Agonists".
Drysdale, et al. J. Med. Chem. 1992, 35, 2573-2581 "Rationally Designed `Dipeptoid' Analogues of CCK. Acid Mimics of the Potent and Selective Non-Peptide CCK-B Receptor Antagonist Cl-988".
Dezube Milana
Hirst Gavin C.
Sugg Elizabeth E.
Glaxo Inc.
Harrington R. Cole
Levy David J.
Springer David B.
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