Modulators of B-lymphocyte activation, myosin-1F...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007210, C435S021000

Reexamination Certificate

active

06890725

ABSTRACT:
The present invention provides compositions and methods for modulating B-lymphocyte activation. Nucleic acids encoding proteins and proteins so encoded which are capable of modulating B-lymphocyte activation are provided. Compositions and methods for the treatment of disorders related to dysfunction or dysregulation of B-lymphocyte activation are also provided. Prophylactics and methods for the prevention of such disorders are also provided. Also provided are compositions and methods for diagnostic and prognostic determination of such disorders. Further provided are assays for the identification of bioactive agents capable of modulating B-lymphocyte activation.

REFERENCES:
patent: 5969102 (1999-10-01), Bram et al.
patent: 6160010 (2000-12-01), Uckun et al.
Crozet et al., “Cloning of the Genes Encoding Two Murine and Human Cochlear Uncoventional Type I Myosins”,Genomics40: 332-341 (1997).

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