Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2011-08-23
2011-08-23
Schultz, Doug (Department: 1633)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C536S026240, C435S090000
Reexamination Certificate
active
08003324
ABSTRACT:
The present invention relates to the use of oxidized nicotinamide adenine dinucleotide (NAD+) or of its reduced form, NADH, as sodium channel modulators. The present invention also relates to the use of compositions containing NAD+or NADH to treat conditions associated with sodium channel current, such as arrhythmia. NAD+is found to increase sodium channel current, while NADH is found to decrease sodium channel current. Thus, conditions that are associated with decreased sodium channel current can be treated with NAD+, while conditions that is associated with increased sodium channel current can be treated with NADH.
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Dinesh Agarwal, P.C.
Emory University
Schultz Doug
U.S. Department of Veterans Affairs
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