Modulation of hair growth

Details Modulation of hair growth Modulation of hair growth

1998-01-20

1999-09-28

Cook, Rebecca

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514270, 514453, 514456, 514718, 514731, A61K 3147

Patent

active

059589469

ABSTRACT:
Mammalian hair growth may be modulated by applying to the skin a compound that induces or activates the conjugation of an androgen.

REFERENCES:
patent: 3426137 (1969-02-01), Philpitt et al.
patent: 4039669 (1977-08-01), Beylar et al.
patent: 4139638 (1979-02-01), Neri et al.
patent: 4161540 (1979-07-01), Neri et al.
patent: 4191775 (1980-03-01), Glen
patent: 4269831 (1981-05-01), Ferrari et al.
patent: 4370315 (1983-01-01), Greff et al.
patent: 4439432 (1984-03-01), Peat
patent: 4508714 (1985-04-01), Cecic et al.
patent: 4517175 (1985-05-01), Iwabuchi et al.
patent: 4720489 (1988-01-01), Shander
patent: 4885289 (1989-12-01), Breuer et al.
patent: 4935231 (1990-06-01), Pigiet
patent: 5095007 (1992-03-01), Ahluwalia
patent: 5096911 (1992-03-01), Ahluwalia et al.
patent: 5132293 (1992-07-01), Shander et al.
patent: 5143925 (1992-09-01), Shander et al.
patent: 5189212 (1993-02-01), Ruenitz
patent: 5271942 (1993-12-01), Haverhagen
patent: 5300284 (1994-04-01), Wiechers et al.
patent: 5364885 (1994-11-01), Ahluwalia et al.
patent: 5411991 (1995-05-01), Shander et al.
patent: 5455234 (1995-10-01), Ahluwalia et al.
patent: 5474763 (1995-12-01), Shander et al.
patent: 5554608 (1996-10-01), Ahluwalia et al.
patent: 5648394 (1997-07-01), Boxall et al.
Pegg et al., "Fundam. Appl. Toxicol.", vol. 32(1):45-32, (1996) (Abstract only).
Andrew G. Messenger, "The Control of Hair Growth: An Overview", The Society for Investigative Dermatology, Inc., 1993.
Green et al., "Cloning and Expression of a Rat Liver Phenobarbital-Inducible UDP-Glucuronosyltransferase (2B12) with Specificity for Monoterpenoid Alcohols", Arch. of Biochem. & Biophysics, vol. 322, Oct. 1, 1995.
Wong et al., "Differential Induction of UDP-Glucuronosyltransferase Activity and Gene Expression in Rat Liver", Pharmaceutical Research, vol. 12, No. 7, 1995.
Sun et al., "Flavonoids increased the activity of Testosterone Glucuronosyltransferase (GT) in prostate cancer cells", Proceedings of the American Association for Cancer Research, vol. 36, Mar. 1995 (Abstract).
Kashfi et al., "Regulation of Uridine Diphosphate Glucuronosyltransferase Expression by Phenolic Antioxidants", Cancer Research, 54, pp. 5856-5859, Nov. 15, 1994.
Pritchard et al., "A Recombinant Phenobarbital-Inducible Rat Liver UDP-Glucoronsyltransferase (UDP-Glucuro-nosyltransferase 2B1) Stably Expressed in V79 Cells Catalyzes . . . " Molecular Pharmacology, 45:42-50, 1993.
Chen et al., "Characterization of a Cloned Human Dihydrotestosterone/Androstanediol UDP-Glucuronosyltrans-ferase and Its Comparison to Other Steroid Isoforms", Biochemistry, vol. 32, No. 40, 10648-57, 1993.
Michael R. Franklin, "Drug Metabolizing Enzyme Induction by Simple Diaryl Pydridines; 2-Substituted Isomers Selectively Increase Only Conjugation Enzyme Activities . . . ", Toxicology and Applied Pharmacology, 111, 1991.
J. Baron, "In situ sites for xenobiotic activation and detoxication: Implications for the differential susceptibility of cells to the toxic . . . ", Progress in Histo-and Cytochemistry, vol. 23, 1991.
Tephyl et al., "UDP-glucuronosyltransferases: a family of detoxifying enzymes", TIPS Reviews, Jul. 1990.
Ritter et al., "Induction of Hepatic Oxidative and Conjugative Drug Metabolism in the Hamster by N-Substituted Imidazoles", Toxicology Letters, 36, pp. 51-59, 1987.
Schweikert et al., Regulation of Human Hair Growth by Steroid Hormones, JCE&M, vol. 38, No. 5, 1974.
Adachi et al., "Human Hair Follicles: Metabolism and Control Mechanisms", Journal of the Society of Cosmetic Chemists, 21, 901-924, Dec. 9, 1970.
Marty E. Sawaya, "Steroid Chemistry and Hormone Controls during the Hair Follicle Cycle", Annals New York Academy of Sciences, pp. 376-384 (Undated).
CA 123:4198, Kudlacek et, 1995.
CA 125:293042, Ahlowaha et al, 1996.

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