Modulation of CRE recombinase in the in vivo cloning of DNA

Details Modulation of CRE recombinase in the in vivo cloning of DNA Modulation of CRE recombinase in the in vivo cloning of DNA

1994-03-15

1995-07-18

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

4352523, 43525233, C12N 1509, C12N 121

Patent

active

054340667

ABSTRACT:
Methods and recombinant vectors suitable for accomplishing the in vivo alteration of a nucleic acid molecule are disclosed. The invention in particular discloses the use of recombinases such as Cre to accomplish in vivo recombination.

REFERENCES:
patent: 4959317 (1990-09-01), Sauer
Weaver et al. (1989), Genetics (Wm. C. Brown Publishers, Dubuque, Iowa) pp. 194-203.
Amann et al. (1983), Gene 25: 167-178.
Hamilton, D. et al., J. Mol. Biol. 178:481-486 (1984).
Hoess, R. et al., Proc. Natl. Acad. Sci. (U.S.A.) 79:3398-3402 (1982).
Abremski, K. et al., J. Biol. Chem. 259:1509-1514 (1984).
Abremski, K. et al., Cell 32:1301-1311 (1983).
Sternberg, N. et al., J. Mol. Biol. 187:197-212 (1986).
Sternberg, N. et al., Cold Spring Harbor Symp. Quant. Biol. 45:297-309 (1981).
Hoess, R. H. et al., Proc. Natl. Acad. Sci. (U.S.A.) 81:1026-1029 (1984).
Sauer, B. et al., Gene 70:331-341 (1988).
Palazzolo, M. J. et al., Gene 88:25-36 (1990).
Elledge, S. J. et al., Proc. Natl. Acad. Sci. (U.S.A.) 88:1731-1735 (1991).
Stratagene (San Diego, Calif.) publication: ".lambda.ZAP" gene cloning system.
Sauer, B. et al., New Biol. 2:441-449 (1990).
Sauer, B., Molec. Cell. Biol. 7:2087-2096 (1987).
Abeles, A., J. Biol. Chem. 261:3548-3555 (1986).
Austin, S. et al., Cell 60:351-354 (1990).
Abeles, A. et al., Proc. Natl. Acad. Sci. (U.S.A.) 88:9011-9015 (1991).
Sauer, B. et al., Nucl. Acids Res. 17:147-161 (1989).
Hoess, R. et al., Cold Spring Harb. Symp. Quant. Biol. 49:761-768 (1984).
Abremski, K. et al., J. Biol. Chem. 261:391-396 (1984).
GIBCO BRL Catalogue and Reference, p. 768 (1992).

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