Modulation of animal cellular responses with compositions contai

Details Modulation of animal cellular responses with compositions contai Modulation of animal cellular responses with compositions contai

1989-06-06

1990-08-14

Hazel, Blondel

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using tissue cell culture to make a protein or polypeptide

424 854, C12P 2100, A61K 3766, C07K 1526

Patent

active

049487302

ABSTRACT:
Compositions and methods for their use in modulating animal cellular responses are disclosed. The compositions include as an active agent an effective amount of an 8-substituted guanine derivative bonded 9-1' to an aldose having 5 or 6 carbon atoms in the aldose chain. The composition includes a diluent amount of a physiologically tolerable carrier. The guanine derivative is free of electrically charged funtionality, while the 8-substituent has an electron withdrawing inductive effector greater than that of hydrogen and contains fewer than about 15 atoms. Anmimal cellular responses are modulated by contacting the cells with a composition of this invention.

REFERENCES:
patent: 3498970 (1970-03-01), Yamodo et al.
Goodman et al., Proc. Natl. Acad. Sci., vol. 78, pp. 7604-7608, 1981.
Goodman et al., J. Immunology, vol. 128, pp. 2399-2404, 1982.
Chemical Abstracts, vol. 71, No. 25, Abstract No. 119619g, 1983.
Chemical Abstracts, vol. 99, No. 5, Abstract No. 3654g, 1983.
Chemical Abstracts, vol. 98, No. 3, Abstract No. 15346g, 1983.

Affiliated with

Also associated with

Rating

Modulation of animal cellular responses with compositions contai does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Modulation of animal cellular responses with compositions contai, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modulation of animal cellular responses with compositions contai will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-462563