Multicellular living organisms and unmodified parts thereof and – Nonhuman animal – Transgenic nonhuman animal
Reexamination Certificate
2005-08-09
2005-08-09
Woitad, Joseph (Department: 1632)
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
Transgenic nonhuman animal
C435S325000
Reexamination Certificate
active
06927317
ABSTRACT:
The invention provides genetically-modified non-human mammals and genetically-modified animal cells containing a disrupted RAMP1, RAMP2, or RAMP3 gene. Also provided by the invention are methods of screening for agents that modulate the activity or expression of a RAMP and methods of treating mammals to modulate liver function and/or muscle metabolism.
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McNeish John D.
Soeller Walter C.
Thompson John F.
Benson Gregg C.
Bertoglio Valarie
Martin Deborah A.
Pfizer Inc.
Richardson Peter C.
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