Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...
Reexamination Certificate
2002-06-05
2009-06-30
Jiang, Dong (Department: 1647)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
C424S141100, C424S184100
Reexamination Certificate
active
07553484
ABSTRACT:
The invention relates to methods and compositions for treating neural damage caused by injury or disease, by enhancing neural outgrowth and/or repair responses in the nervous system. Preferably, the methods and compositions utilize agents which interfere with the ability of the major histocompatibility complex (MHC) Class I molecule (MHC I) to inhibit neurite outgrowth. Such agents include antibodies directed to MHC I, MHC I fragments and/or analogs, and agents which interfere with MHC I interaction with its neuronal receptor and the receptor's signaling pathway.
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Remington, Pharmaceutical Scien
Hanssen Lorraine
Kaufman Daniel L.
Zekzer Dan
Bingham & McCutchen LLP
Jiang Dong
The Regents of the University of California
Wegert Sandra
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