Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1999-03-30
2000-09-19
Jarvis, William R. A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514396, 514399, 514534, 514543, 514563, A61K 3141, A61K 31415, A61K 3124, A61K 31235, A61K 31195
Patent
active
061212997
ABSTRACT:
This invention relates to methods of modulating inflammation in mammals. Inflammation is modulated by regulating the cytochrome P-450 pathway. Inflammation is reduced by treating the subject with substances, such as bezafibrate and clofibrate, which induce the P-450 pathway. Inflammation is promoted by treating the subject with substances, such as proadifen, econazole, and clotrimazole, which inhibit the cytochrome P-450 pathway.
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Kluger Matthew J.
Kozak Wieslaw
Tesfaigzi Yohannes
Baker Rod D.
Jarvis William R. A.
Lovelace Respiratory Research Institute
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