Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2011-01-18
2011-01-18
Belyavskyi, Michail A (Department: 1644)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
Reexamination Certificate
active
07872103
ABSTRACT:
The invention provides methods for modulating the immune system using anti-CD83 antibodies that can influence CD83 function.
REFERENCES:
patent: 5316320 (1994-05-01), Breaker
patent: 5316920 (1994-05-01), Tedder et al.
patent: 5766570 (1998-06-01), Tedder et al.
patent: 6068984 (2000-05-01), Tedder et al.
patent: 6900016 (2005-05-01), Venter et al.
patent: 2006/0083740 (2006-04-01), Ramsdell et al.
patent: 95/29236 (1995-11-01), None
patent: 97/29781 (1997-08-01), None
patent: 02/074921 (2002-09-01), None
patent: 03/038072 (2003-05-01), None
patent: 03/040170 (2003-05-01), None
patent: 03/045318 (2003-06-01), None
Armitage, R.J et al., Evidence for a Function Role of CD83 in T- and B- Cell Responses,Tissue Antigens, 48(4-2): 453FF, 1996.
Bancroft et al., Cyokine Production in BALB/c Mice Immunized with Radiation Attenuated Third Stage Lavae of the Filarial Nematode,The Journal of Immunology, 150(4):1395-1402, 1993.
Chen et al., In vitro induction of T cell anergy by block B7 and early T cell costimulatory molecule ETC-1/B7-2,Immunity, 1:147-154m 1994.
Clerici et al., A TH1→ TH2 switch is a critical step in the etiology of HIV infection.,Immunology Today, 14(3): 107-111, 1993.
Cramer, S.O. et al., Activation-Induced Expression of a Murine CD83 on T Cells and Identification of a Specific CD83 Ligand on Murin B Cells,International Immunology, 12(9): 1347-1351, 2000.
Dallman, Cytokines and transplantation: Th1/Th2 regulation of the immune response to solid organ transplants in the adult,Current Opinion in Immunology, 7:632-638, 1995.
Dreher, K.L. et al., cDNA Clone Encoding a Complete Rabbit Immunoglobulin K Light Chain of b4 Allotype,Pro Natl. Acad. Sci. USA, 80: 4489-4493, Jul. 1983.
Else et al., Cytokine-mediated regulation of chornic intestinal helminth infection,J. Exp. Med., 179L 347-351, 1994.
Fauci, The human immunodeficiency virus: infectivity and mechanisms of pathogenesis,Science, 239:617-622, 1988.
Fowler et al., Donor Lymphoid Cells of Th2 Cytokine Phenotype Reduce Lethal Graft Versus Host Disease and Facsiltate Fully Allogeneic Cell Transfers in Sublethally Irradiated Mice,Advances in Bone Marrow Purging and Processing: Fourth International Symposium, 533-540, 1994.
Fowler et al., Donor CD4-Enriched Cells of Th2 Cytokine Phenotype Regulate Graft-Versus-Host Disease Without Impairing Allogeneic Engraftment in Sublethally Irradiated Mice,Blood, 84(10): 3540-3549, 1994.
Frasca L et al. 2006. CD38 orchestrates migration, survival and Th1 immune response of human mature dendritic cells,Blood, 107(6): 2392-2399.
Fujimoto, Y. et al., CD83 Expression Influences CD4+ T Cell Development in the Thymus,Cell, 108: 755-767, 2002.
Fujimoto, Y. et al., Dendritic Cell CD 83 Provides a Progression Signal Required for CD4+ T Cells Positive Selection in the Thymus,FASEB Journal,15(4): A672, 2001.
Gorczynski et al., Interleukim 12 in combination with anti-interleukin 10 reverses graft prolongation after portal venous immunization,Transplantation, 60(11): 1337-1341, 1995.
Grzych et al., Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni,The Journal of Immunology, 146(4): 1322-1329, 1991.
Heinzel et al., Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets,J. Exp. Med., 169:59-72, 1989.
Hsieh-Ma, S.T. et al.,Clinical Immunology and Immunopathology, 80(2) 185-193, 1996.
Hock, B.D. et al., A Soluble Form of CD83 is Release from Activated Dendritic Cells and B Lymphocytes, and Is Detectable in Normal Human Sera,International Immunology, v. 13 pp. 959-967 2001.
Jaton, J.C., Completion of the Analysis of the Primary Structure of the Variable Domain of the Hmogeneous Rabbit Antibody to Type III Pneumococcal Polysaccharide,Biochem J.143: 723-732, 1973.
Khoury et al., Oral tolerance to myelin basic protein and natural recovery fro experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming grown factor beta, interleukin 4, and prostaglandin E expression in the brain,J. Exp. Med., 176:1355-1364, 1992.
Knappik et al.,Journal of Molecular Biology, 2000.
Kuchroo et al., Cytokines and adhestion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis,The Journal of Immunology, 151(8): 4371-4382, 1993.
Kullberg et al., Infection with Schistosoma mansoni alters Th1/Th2 cytokine responses to a non-parasite antigen,The Journal of Immunology, 148(10):3264-3270, 1992.
Leonard et al., Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12,J. Exp. Med., 181:381-386, 1995.
Levy et al., Adminsitration of intragraft interleukin-4 prolongs cardiac allograft survival in rates treated with donor-specific transfusion/cyclosporine,Transplantation, 60(5): 405-406, 1995.
Locksley et al., Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function,T-Cell Subsets, A58-A61, 1991.
Ma, J. K-C and Hein, M.B.Tibtech13:522-527, 1995.
Maeda et al., Adoptive transfer of a Th2-like cell line prolongs MHc class II antigen disparate skin allograft survival in the mouse,International Immunology, 6(6): 855-862, 1994.
Marmor, M.D. and Julius , M.,Blood98(5): 1489-1497, 2001.
Morrissey et al., Granulocyte-macrophage colony-stimulating factor augments the primary antibody response by enhanving the function of antigen-presenting cells,The Journal of Immunology, 139(4): 1113-1119, 1987.
Mosmann et al., Two types of murin helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins,The Journal of Immunology, 136(7): 2348-2357, 1986.
Munster, D.J. et al., CD83 Antigen: A Potential New Target for Immunosuppression,Blood, 100(11): Abstract No. 3694, 2002.
Paul et al., Lymphocute Responses and Cytokines,Cell, 76: 241-251, 1994.
Paul, Fundamental Immunology, (textbook), 1999, under the heading “Immunoglobulins: Structure and Function,” pp. 37,43,58 and 59.
Pearce et al., Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni,J. Exp. Med., 173:159-166, 1991.
Pearlman et al., Inducation of Murin T-Helper-Cell Reponses to the Filarial NamatodeBrugia malayi., Infection and Immunity, 61(3): 1105-1112, 1993.
Pisa et al., Selective expression of interleukin 10, interferon gamma, and granulocyte-macrophage colony-stimulating factor in ovarian cancer biopsies,Proc. Natl. Acad. Sci. USA, 89:7708-7712, 1992.
Racke et al., Cytokine-induced immune deviation as a therapy of inflammatory autoimmune disease,J. Exp. Med., 180:1961-1966, 1994.
Rapoport et al., Interleukin 4 reverses T cell proliferate unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice,J. Exp. Med., 178:87-99, 1993.
Rudikoff et al., Singel amino acid substitution altering antigen-binding specificity,Proc Natl Acad Sci USA, 1982 vol. 79 p. 1979.
Sadick et al., Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent interferon gamma-independent mechanism,J. Exp. Med., 171:115-127, 1990.
Scholler, N. et al., CD83 is a Sialic Acid-Binding IG-Like Lection (Siglec) Adhesion Receptor that Binds Monocytes and a Subset of Activated CD8+ T Cells,Immunology, 166: 3865-3872, 2001.
Schwartz et al., Autoimmunity and Autoimmune Diseases,Fundamental Immunology, Second Edition: New York, 819-856, 1989.
Seder et al., Acquisition of lymphokine-producing phenoltype by CD4+ T cells,Annu. Rev. Immunol., 12:635-673, 1994.
Shearer et al., T helper cell immune dysfunction in asymptomatic, HIV-1-seropositive individuals: the role of TH1-TH2 cross regulation,Chem. Immunol., 54:21-43, 1992.
Simon et al., Divergent T-Cell Cytokine Patterns in Inflammatory Arthritis,Proc. Natl. Acad. Sci. USA, 91(18):8562-8566, 1994.
Takeuchi et al., Heart Allografts in Murine Systems,Transplantation, 53(6): 1281-1294, 199
Andrews Dawn
Chen Yuching
Garcia-Martinez Leon Fernando
Belyavskyi Michail A
Celltech R & D Limited
K&L Gates LLP
Winger, Ph.D. C. Rachal
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