Modulating body/cranial hair growth with lipoxygenase/cyclooxyge

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice

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424 701, 424465, 514880, A61K 700

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active

059286547

ABSTRACT:
The loss of body/cranial hair is promoted and/or its growth is slowed/prevented by topically and/or systemically administering to an individual in need of such treatment respectively effective amounts at least one lipoxygenase inhibitor and at least one cyclooxygenase inhibitor, or alternatively, an effective amount of an active agent that is both a lipoxygenase inhibitor and a cyclooxygenase inhibitor.

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Baumann et al, Falvonoids and related compounds as inhibitors of arachidonic acid peroxidation, Prostaglandins, vol. 20, No. 4, pp. 627-639, Nov. 1980.
Chemical Abstracts, vol. 115, No. 20, Nov. 18, 1991, Columbus, Ohio, USA, Abstract No. 214519, C. Watanabe: "Hair tonics containing hormones and ginkgo extracts," XP002024235 & JP 03 161 426 A (Kobayashi Kose Co., Ltd.) Jul. 11, 1991.
Chemical Abstracts, vol. 112, No. 22, May 28, 1990, Columbus, Ohio, USA, Abstract No. 204493, Y. Tomita: "Skin-lightening cosmetics containing antihistaminics, mas cell degranulation inhibitors, cyclooxygenase inhibitors, or lipoxygenase inhibitors." XP002024236 & JP 02 017 115 A (Shiseido Co., Ltd.) Jan. 22, 1990.

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