Modular assembly of antibody genes, antibodies prepared thereby

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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4351723, 43525233, 435 696, 4241331, A61K 39395, C12N 1513, C12N 121

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056189206

ABSTRACT:
The invention relates to the secretion of heavy chain immunoglobulin fragments and light chain immunoglobulins from prokaryotic hosts using a prokaryotic secretion signal peptide wherein the heavy chain fragments and light chains are capable of associating to form an antigen binding antibody fragment.

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