Modified vitamin K-dependent polypeptides

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S333000, C530S384000, C530S412000, C424S094640, C424S529000, C435S212000, C435S226000

Reexamination Certificate

active

07314917

ABSTRACT:
The invention provides vitamin K-dependent polypeptides with enhanced membrane binding affinity. These polypeptides can be used to modulate clot formation in mammals. Methods of modulating clot formation in mammals are also described.

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