Modified vaccinia ankara virus vaccine

Details Modified vaccinia ankara virus vaccine Modified vaccinia ankara virus vaccine

2011-07-05

2011-07-05

Mosher, Mary E (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant virus encoding one or more heterologous proteins...

C424S232100, C435S235100, C435S320100

Reexamination Certificate

active

07972605

ABSTRACT:
The present invention relates, in general, to vaccines and, in particular, to a modified vaccinia Ankara (MVA) virus, to a composition comprising such a virus and to methods of using same to induce an immune response.

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Ifeanyi Okeke et al, “Comparative sequence analysis of A-type inclusion (ATI) and P4c proteins of orthopoxviruses that produce typical and atypical ATI phenotypes”, Virus Genes, published online: Jun. 16, 2009.
Meisinger-Henschel et al, “Introduction of the Six Major Genomic Deletions of Modified Vaccinia Virus Ankara (MVA) into the Parental Vaccinia Virus Is Not Sufficient to Reproduce an MVA-Like Phenotype in Cell Culture and in Mice”, Journal of Virology 84(19):9907-9919 (2010).
Vaccinia virus P4c (p4c) gene, complete cds, GenBank: AF464893.2, Accession No. AF464893, Version AF464893.2 GI:311977070.

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