Chemistry: molecular biology and microbiology – Apparatus
Reexamination Certificate
2006-07-31
2010-06-08
Tate, Christopher R (Department: 1651)
Chemistry: molecular biology and microbiology
Apparatus
C424S085100, C424S093700, C424S400000, C424S428000, C424S486000, C424S520000, C514S002600
Reexamination Certificate
active
07732190
ABSTRACT:
Compositions, methods of manufacture and methods of treatment for post-myocardial infarction are herein disclosed. In some embodiments, the composition includes at least two components. In one embodiment, a first component can include a first functionalized polymer and a substance having at least one cell adhesion site combined in a first buffer at a pH of approximately 6.5. A second component can include a second buffer in a pH of between about 7.5 and 9.0. A second functionalized polymer can be included in the first or second component. In some embodiments, the composition can include at least one cell type and/or at least one growth factor. In some embodiments, the composition(s) of the present invention can be delivered by a dual bore injection device to a treatment area, such as a post-myocardial infarct region.
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Basu Shubhayu
Michal Eugene
Trollsas Olof Mikael
Advanced Cardiovascular Systems Inc.
Blakely , Sokoloff, Taylor & Zafman LLP
Kosar Aaron J
Tate Christopher R
LandOfFree
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