Modified tripeptides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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530331, 514424, 514428, 544372, 544384, 548531, 548536, 548537, 548542, 548568, 548572, 560 25, 560 29, 560153, 560159, 560160, 560169, 530315, A61K 3134, C07D20709, C07D20712, C07D20748

Patent

active

045968195

ABSTRACT:
Modified oxytocin-vasopressin di- or tri-peptides wherein an amide group is replaced by a group selected from ##STR1## --CH.sub.2 NH--, --CH.sub.2 O--, --CH.sub.2 S--, --CH.sub.2 SO--, --CH.sub.2 SO.sub.2 --, --CH.sub.2 CH.sub.2 -- and --CH.dbd.CH-- are described as well as methods for their manufacture, pharmaceutical compositions and methods for treatment, especially of cognitive disorders, depression, morphine dependency and parkinsonism by adjunctive therapy.

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patent: 4325943 (1982-04-01), Natarajan et al.
patent: 4371699 (1983-02-01), Ohashi et al.
patent: 4402969 (1983-09-01), Greenlee et al.
patent: 4425333 (1984-01-01), Iwao et al.
patent: 4431645 (1984-02-01), Smith et al.

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