Modified trichokirin and their preparation for use in conjugates

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Plant proteins – e.g. – derived from legumes – algae or...

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530350, 530402, 530408, 530409, 530410, 530411, 530395, C07K 1500

Patent

active

051625024

ABSTRACT:
The present invention relates to a novel glycoprotein, extracted from the seeds of Trichosanthes kirilowii, called: trichokirin, as well as to its modified derivatives containing a free or blocked SH group. It relates to a process for its preparation, to its use and to pharmaceutical compositions in which it is present.

REFERENCES:
patent: 4985541 (1991-01-01), Maraganore et al.
Olsnes et al., Pharmac. Ther. vol. 15, 1982, pp. 355-381.
Ma et al., Chem. Abst. vol. 104(3) #173074, 1985.
Yeung et al., Chem. Abst vol. 107(5) #33362a, 1987.

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