Modified substrates for the attachment of biomolecules

Stock material or miscellaneous articles – Composite – Of quartz or glass

Reexamination Certificate

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C428S446000, C428S447000, C428S448000, C427S387000, C427S452000, C427S489000, C427S503000, C427S515000, C427S527000, C427S574000, C427S585000, C536S024300, C435S006120

Reexamination Certificate

active

06916541

ABSTRACT:
The present invention relates to a substrate for attachment of biomolecules. The substrate is coated with a multiamino organosilane. If desired, the substrate can be further modified prior to coating with a multiamino organosilane. Optional surface modifications include coating the substrate with SiO2or leaching with acid to form a SiO2rich layer. DNA, nucleic acids, or any bimolecules can be attached to the coated substrates of the invention. Although a variety of substrates are contemplated, the preferred substrate is a low self-fluorescent glass.

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