Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1992-10-13
1998-01-06
Prouty, Rebecca E.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 691, 43525231, 4352523, 536 231, 536 234, 536 232, 536 235, 536 237, 530350, 530351, C12N 1509, C12N 121, C12N 1524, C12N 1556
Patent
active
057053626
ABSTRACT:
The present invention describes a method for reducing processing ambiguity of signal peptidases. Specifically, the C-terminus of a signal sequence is mutated in a such a manner that the secreted protein contains the correct N-terminal amino acid.
Furthermore, the present invention provides an hIL-3 which is essentially homogenous at its N-terminus.
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Bonekamp AlfonsusJohannes
Van Tilborg Marcellis Wilhelmus Elisabeth Maria
Gist-brocades, N.V.
Prouty Rebecca E.
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