Modified release oral pharmaceutical composition and method for

Details Modified release oral pharmaceutical composition and method for Modified release oral pharmaceutical composition and method for

1996-12-20

1999-12-21

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424462, 424495, 424497, A61K 958, A61K 962

Patent

active

060045817

ABSTRACT:
Modified release pharmaceutical composition and method for the treatment of inflammatory bowel diseases (IBD) such as Crohn's disease and Colitis Ulccrosa, said compositions comprising as active the ingredient 5-aminosalicylic acid (5-ASA), and being adapted for modified and targeted release so as to obtain a clinically important localized effect profile of 5-ASA by means of releasing an appropriate amount of 5-ASA in both the small and large bowel.

REFERENCES:
patent: 4496553 (1985-01-01), Halskov
patent: 4960765 (1990-10-01), Halskov
patent: 4980173 (1990-12-01), Halskov
patent: 5294448 (1994-03-01), Ring et al.
patent: 5401512 (1995-03-01), Rhodes et al.
patent: 5716648 (1998-02-01), Halskov et al.
Bechgaard, H., Acta Pharmaceutica Technologica 28(2), 1982, pp. 149-157.
Fallingborg, J. et al, Aliment. Pharmacol. Therap. (1989) 3, pp. 605-613.
Christensen, L.A. et al, Br. J. Clin. Pharmac. (1987), 23, pp. 365-369.

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