Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2005-05-24
2005-05-24
Kunz, Gary (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C435S069100, C435S069600, C536S023400, C536S023500
Reexamination Certificate
active
06897290
ABSTRACT:
Analogs of regulators of complement activation (RCA) proteins which have altered specificities and affinities for the targets C3b and/or C4b are described. These analogs are obtained by substituting amino acids which affect the complement inhibitory activities of these proteins, substituting, rearranging or adding SCRs (short consensus repeats) or SCR regions to the proteins, deleting amino acid sequences, and combinations thereof.
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Atkinson John P.
Hourcade Dennis
Krych Malgorzata
Hamilton Brook Smith & Reynolds P.C.
Kunz Gary
Washington University
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