Modified radioantibody fragments for reduced renal uptake

Details Modified radioantibody fragments for reduced renal uptake Modified radioantibody fragments for reduced renal uptake

1994-09-20

1997-09-23

Kight, John

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 149, 424 169, 534 10, 534 14, 530300, A61K 5100, A61M 3614

Patent

active

056701322

ABSTRACT:
PEG-modified-Tc-99m-radiolabeled antibody fragments are useful for radioimmunodetection of tumors and infectious lesions and display striking reductions in renal uptake and retention of radioisotope compared to non-PEG-modified fragments.

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