Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1988-05-11
1991-02-05
Teskin, Robin L.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
4351723, 43525234, 435 691, 435877, 4353201, 935 14, 935 82, 935 10, C12N 1500, C12N 936, C12N 996, C12N 999
Patent
active
049904531
ABSTRACT:
A stable mutant form of creatine amidohydrolase is disclosed. This enzyme is formed via expression of altered DNA, which may be in plasmid form. Also disclosed is a method for determining creatinine using the mutant form.
REFERENCES:
patent: 3912588 (1975-10-01), Mollering
patent: 4039384 (1977-08-01), Suzuici
patent: 4692409 (1987-09-01), Kisumi
patent: 4861717 (1989-08-01), Schumacher
Patent Abstracts of Japan 6: 106 (C-108) (984) 6/16/82.
Bryan et al., Proteins: Structure, Function & Genetics 1(4): 326-334 (1986).
Buckel Peter
Schumacher Gunther
Boehringer Mannheim GmbH
Marks Michelle S.
Teskin Robin L.
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