Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2005-01-25
2005-01-25
Brumback, Brenda (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S399000, C424S192100, C424S198100, C435S069700
Reexamination Certificate
active
06846906
ABSTRACT:
The invention provides modified proteins and DNAs of the TGF-β superfamily including modified morphogenic proteins. The proteins of the present invention display altered biological or biochemical attributes. Specifically, the modified proteins are designed through manipulation or exchange of subdomains among two or more members of the superfamily such that certain desired attributes are mixed-and-matched and then exploited therapeutically.
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McCartney John
Oppermann Hermann
Tai Mei-Sheng
Brumback Brenda
Fish & Neave LLP
Haley Jr. James F.
Mangasarian Karen
Seharaseyon Jegatheesan
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