Modified phosphoramidite process for the production of modified

Details Modified phosphoramidite process for the production of modified Modified phosphoramidite process for the production of modified

1997-09-19

1999-05-11

Wilson, James O.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 231, 536 243, 536 2433, 536 253, 536 2531, 536 2532, 536 2533, 536 2534, 435 6, 435 911, C07H1/00;21/00

Patent

active

059028785

ABSTRACT:
The subject matter of the invention is a modified phosphoramidite process for the synthesis of nucleotide sequences. By use of a modified nucleoside phosphoramidite it is possible to produce nucleotide sequences which have a modified phosphate residue.

REFERENCES:
patent: 4415732 (1983-11-01), Caruthers et al.
patent: 4547569 (1985-10-01), Letsinger et al.
patent: 4816569 (1989-03-01), Miyoshi
patent: 5700919 (1997-12-01), Seliger et al.
Thuong et al., Biochime, 67, pp. 673-684, 1985, "Chemical synthesis of natural and modified oligodeoxynucleotides".
Barker et al., J. Biol. Chem., 246, pp. 7135-7147, "Agarose Derivatives of Uridine Diphosphate and N-Acetylglucosamine for the Purification of Galactosyltransferase".
Cuatrecasas, J. Biol. Chem., 245, pp. 3059-3065, 1970, "Protein Purification by Affinity Chromatography".
Jager et al., Biochemistry, 27, pp. 7237-7246, 1988, "Oligonucleotide N-Alkylphosphoramidates: Synthesis and Binding to Polynucleotides".
Bannwarth et al., Tetrahedron Letters vol. 30, No. 12, pp. 1513-1516, 1989, "A simple specific labelling for oligonucleotides by bathophenanthroline-Ru" Complexes as nonradioactive label molecules.
Asseline et al., Nucleosides & Nucleotides, 7, pp. 431-455, 1988, "Oligothymidylates Substitues Par Un Derive De L'Acridine en Position 5', A la fois en Position 5' et 3' ou sur un Phosphate" Internucleotidique.
Gait, Oligonucleotide Synthesis, IRL Press, Oxford, 1994, pp. 35-49, "Solid-phase Synthesis of Oligodexyribonucleotides by the Phosphite-triester Method".
Hamamoto et al., Chemistry Letters, pp. 1401-1404, 1986, "New Approach to the Synthesis of Deoxyribonucleoside Phosphoramidite Derivatives".
Zuckerman, Nucleic Acids Research, vol. 15, No. 13, pp. 5305-5321, 1987, "Efficient methods for attachment of thiol specific probes to the 3'-ends of synthetic oligodeoxyribonucleotides".

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