Modified papilloma virus L2 protein and VLPs formed therefrom

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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Details

4241991, 435 691, 435 693, 4352351, 435440, 536 2372, 935 65, A61K 3912, C12N 700, C12N 701

Patent

active

059938218

ABSTRACT:
The invention, in one aspect, is directed to a modified papilloma virus L2 protein which does not bind DNA or which has a substantially impaired ability to bind DNA compared to wild-type papilloma virus L2 protein. The invention is also directed to a method of producing one or more virus-like particles comprising a modified papilloma virus L2 protein according to the invention. The invention also resides in virus-like particles produced from this method.

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