Modified oligonucleotides and applications thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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Details

C536S024300, C536S024330, C435S006120, C435S091100, C435S091200

Reexamination Certificate

active

07943752

ABSTRACT:
Disclosed, among other things, are primers containing certain modified nucleobases in the 3′ terminal region of the primers that provide reduced formation of primer-dimers during amplification reactions, and various methods of use thereof.

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USPTO issued Notice of Allowance and Fees Due mailed Dec. 2, 2008 in U.S. Appl. No. 11/250,192 filed Oct. 12, 2005.
USPTO issued Non-Final Rejection mailed Jul. 18, 2007 in U.S. Appl. No. 11/250,192 filed Oct. 12, 2005.
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Sella, F. et al., “Synthesis of the b-D-deoxyribofuranoside of 6-amino-1H-pyrazolo[3,4-dJpyrimidin-4(5H)-one—a new isoster of 2'-deoxyguanosin”,Heterocyclesvol. 23(10) 1985 , pp. 2521-2524.
USPTO issued Final Rejection mailed Mar. 17, 2008 in U.S. Appl. No. 11/250,192, 9 pp.
USPTO issued Notice of Allowance mailed Aug. 15, 2008 in U.S. Appl. No. 11/250,192, 5 pp.
Information Disclosure Statement dated Nov. 11, 2008 as filed in U.S. Appl. No. 11/250,192, 4 pp.
USPTO issued Notice of Allowance mailed Dec. 2, 2008 in U.S. Appl. No. 11/250,192, 6pp.

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