Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Reexamination Certificate
2007-02-20
2007-02-20
Guzo, David (Department: 1636)
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
C424S093100, C424S093600, C435S320100, C435S455000, C435S456000, C435S091100, C435S091300, C435S091320, C435S091330, C536S023100, C536S023200, C536S023400, C536S023720, C536S024100
Reexamination Certificate
active
10221993
ABSTRACT:
The invention provides a nodavirus RNA1 molecule modified to include a heterologous insertion which is downstream of its replicase ORF and, preferably, its B2 ORF. The insertion preferably comprises one or more protein-coding regions. The modified RNA1 may be packaged in a VLP, such as a papillomavirus VLP. The small size of nodavirus RNA1 makes it ideal for HPV packaging.
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Bensi Giuliano
Zippo Alessio
Chiron S.r.l.
Harbin Alisa A.
Lee Helen
Robins Roberta L.
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