Modified neurotoxin derived from Naja genus snake venom

Details Modified neurotoxin derived from Naja genus snake venom Modified neurotoxin derived from Naja genus snake venom

1977-07-22

1978-11-21

Rosen, Sam

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

A61K 3558

Patent

active

041266765

ABSTRACT:
The present invention relates to a composition, a process of production thereof, and a method for treatment of neurological diseases, and especially to the treatment of such diseases as amyotropic lateral sclerosis, by administering detoxified but neurotropically active modified snake venom neurotoxin composition derived from the venom of the Naja genus, where the composition exhibits at least a 30% inhibition of viral plaques in the Semliki Forest virus test and a bioassay shows the composition to be atoxic.

REFERENCES:
patent: 3888977 (1975-06-01), Sanders

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