Modified mite allergen and pharmaceutical uses thereof

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

Reexamination Certificate

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C530S350000

Reexamination Certificate

active

07846449

ABSTRACT:
The present invention provides a modifiedDermatophagoides pteronyssinusallergen Der p 5 protein which has ability to inhibit IgE binding when exposed against to the antigen. A method for treating allergy comprising administrating a therapeutically effective dose of the modifiedD. pteronyssinusallergen Der p 5 protein to a subject suffering from allergy Der p 5 is also provided.

REFERENCES:
patent: 6187311 (2001-02-01), Nishiyama et al.
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Beezhold et al., “Mutational analysis of the IgE epitopes in the latex allergen Hev b 5”,J. Allergy Clin Immunol, Jun. 2001, pp. 1069-1076, vol. 107, No. 6.
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