Modified microbially-produced cellulose gel with human epidermal

Details Modified microbially-produced cellulose gel with human epidermal Modified microbially-produced cellulose gel with human epidermal

1995-12-05

1996-09-24

Sayala, Chhaya D.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Animal or plant cell

424 931, 424422, 424445, 424488, 424574, 623 15, 536 56, 435 11W, 4352402, 43524023, 435240243, 435948, A01N 6300, A61F 1300, A61F 210, A61L 1500, A61K 914, A61K 3536, C08B 100, C12N 102

Patent

active

055588611

ABSTRACT:
Disclosed is a gel of microbially-produced cellulose, characterized in that the microbially-produced cellulose is modified by (1) physically or chemically bonding an animal cell adhesive protein to the cellulose, and/or (2) substituting hydrogen atoms of at least parts of hydroxyl groups of the cellulose with a positively or negatively charged organic group. This gel is valuable as a carrier for mass culture of animal cells or as a medical vulnerary cover.

REFERENCES:
patent: 4036693 (1977-07-01), Levine et al.
patent: 4464468 (1984-08-01), Avrameas et al.
Talbot et al, "Utilisation of DEAE-cellulose as a microcarrier material", CA93, # 67435j 1985.
Reuveny et al, "Newly developed microcarrier culturing systems" CA. 104, # 107787e Mar., 1986.
Patent Abstracts of Japan, vol. 10, No. 178 (C-355) [2234] Jun. 21, 1988.

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