Modified live pseudorabies viruses

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...

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424 89, 435236, C12N 700, A61K 39205

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active

045144974

ABSTRACT:
Temperature-resistant pseudorabies viruses which fail to produce any functional TK as a result of mutagen-induced mutation and temperature-resistant pseudorabies viruses which fail to produce any functional TK as a result of a deletion in the tk gene, vaccines containing same, methods for production of same and methods for use of same.

REFERENCES:
patent: 4049794 (1977-09-01), Straub
Skoda-Acta. Virol., vol. 6, (1962), p. 189.
Skoda et al.-Acta. Virol., vol. 8, (1964), pp. 1-9.
Tenser et al.-J. Gen. Virol., vol. 64, (1983), pp. 1369-1373.
Tenser et al.-J. Clin. Microbiol., vol. 17, No. 1, (1983), pp. 122-127.
Kit et al.-Prog. Med. Virol., vol. 21, (1975), pp. 13-34.
Ben-Porat-Virology, vol. 127, (1983), pp. 194-204.
Feldman et al.-Journal of General Virology, vol. 54, (1981), pp. 333-342.

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