Modified lipase

Details Modified lipase Modified lipase

1984-12-31

1987-02-24

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435135, 435188, 435198, C12P 764, C12P 762, C12N 996, C12N 920

Patent

active

046457410

ABSTRACT:
A modified lipase, comprising lipase molecules which are partially substituted with an active derivative of a polyalkylene glcyol having a hydrophobic group at the terminal end.

REFERENCES:
patent: 4179337 (1979-12-01), Davis et al.
Abuchowski et al, "Alteration of Immunological Properties of Bovine Serum Albumin by Covalent Attachment of Polyethylene Glycol" J. Bio. Chem., vol. 252, No. 11, pp. 3578-3581 (1977).
Abuchowski et al, "Effect of Covalent Attachment of Polyethylene Glycol on Immunogenicity and Circulating Life of Bovine Liver Catalase" J. Bio. Chem. vol. 252, No. 11, pp. 3582-3586, (1977).
T. Yoshimoto et al, "Modified Lipase having High Stability and Various Enzymic Activities in Benzene, and its Re-use by Recovering from Benzene Solution", Biotechnology Letters, vol. 6, No. 6, pp. 337-340 (1984).
Yuji Inada et al, "Ester Synthesis Catalyzed by Polyethylene Glycol-Modified Lipase in Benzene", Biochemical and Biophysical Research Communications, vol. 122, No. 2, (1984), pp. 845-850.
K. Takahashi et al, "Modified Lipoprotein Lipase Catalyzes Ester Synthesis in Benzene", Enzyme 32, pp. 235-240, (1984).

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