Modified lambda bacteriophage

Details Modified lambda bacteriophage Modified lambda bacteriophage

1995-12-08

1997-09-02

Allen, Marianne P.

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

435239, 536 2372, 530402, C12N 702, C12N 701, C07H 2104, C07K 14005

Patent

active

056630697

ABSTRACT:
Disclosed is a protein construct including a chemically modified lambdoid tail protein having a chemically reactive amino acid residue linked to a target molecule. Also disclosed is an infective lambdoid bacteriophage displaying on its outer surface the chemically modified tail protein. In addition, methods of detecting a molecule-of-interest in a solution and methods of detecting cells producing a molecule-of-interest which utilize the infective lambdoid bacteriophage having the chemically modified tail protein are disclosed.

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