Modified HIL-6

Details Modified HIL-6 Modified HIL-6

1990-12-21

1993-11-23

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Lymphokine

Interleukin

530351, 530406, 530410, C07K 1506, A61K 3702

Patent

active

052642097

ABSTRACT:
Provided are PEGylated "interleukin-6" derivatives (PEG IL-6) having an extended plasma half-life, as well as enhanced in-vivo IL-6 biological activities.
Methods for producing the modified glycosylated and unglycosylated IL-6 proteins or polypeptides, as well as, for their use in treating hematopoietic disorders and difficiencies, particularly acute thrombocytopenia, are also provided.

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