Modified gangliosides and the functional derivatives thereof

Details Modified gangliosides and the functional derivatives thereof Modified gangliosides and the functional derivatives thereof

1990-11-13

1993-11-23

Husarik, Nancy S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 25, 514 53, 514 61, 536 41, 536 53, 536 551, 536123, A61K 31435, A61K 31715, C07N 506

Patent

active

052644243

ABSTRACT:
N-acyl-N,N'-di-lysogangliosides, N'-acyl-N,N'-di-lysogangliosides and N,N'-diacyl-N,N'-di-lysogangliosides, in which the acyl groups are derived from an organic acid of the aliphatic, aromatic, araliphatic, alicyclic or heterocyclic series and in which at least one of the two acyl groups is not aliphatic, and their preparation are disclosed. Also disclosed is the preparation of the esters, inner esters, amides and hydroxy peracylates of these compounds and salts thereof. These compounds are useful in the treatment of pathologies of the central and peripheral nervous systems.

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