Modified form of the R(-)-N-(4,4-di(3-methylthien-2-yl)but-3-eny

Details Modified form of the R(-)-N-(4,4-di(3-methylthien-2-yl)but-3-eny Modified form of the R(-)-N-(4,4-di(3-methylthien-2-yl)but-3-eny

1997-06-10

1999-09-28

Chang, Ceila

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546212, A61K 31445, C07D40914

Patent

active

059589515

ABSTRACT:
The present invention provides R(-)-N-(4,4-di(3-methylthien-2-yl)but-3-enyl)-nipecotic acid hydrochloride in its pure and stable anhydrous form.

REFERENCES:
patent: 5010090 (1991-04-01), Gronvald et al.
McGraw et al. "The identification and characterization of polymorphism in tiagabine HCI bulk drug" Derwent abst 95-05633, 1994.
Andersen et al., J. Med. Chem., vol. 36, pp. 1716-1725 (1993).

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