Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1989-03-07
1992-01-07
Moskowitz, Margaret
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530324, 530855, 435 692, C07K 710, A61K 3764
Patent
active
050792296
ABSTRACT:
Novel elgin mutants that differ from the natural eglins B and C by the replacement of one, two or three amino acids in the region of the active center (amino acids 45 and 46, Leu-Asp) by other amino acids are provided. The mutants, which can be produced by recombinant genetic engineering, have valuable pharmacological properties.
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Grutter Markus G.
Heinz Dirk
Liersch Manfred
Ciba-Geigy Corporation
Foley Shawn P.
Moskowitz Margaret
Ossanna Nina
Villamizar JoAnn
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