Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2005-08-30
2005-08-30
Housel, James C. (Department: 1648)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S023100, C435S320100, C424S184100, C424S192100, C424S196110, C424S197110, C424S264100
Reexamination Certificate
active
06936707
ABSTRACT:
There is provided a DNA molecule derived from a prokaryotic cell in which at least one of the DNA regions encoding NXB (N is asparagine, X is any amino acid other than proline, and B is serine or threonine) has been modified so that no N-glycosylation occurs during the expression in a eukaryotic cell, and since the DNA molecule has been modified at the N-glycosylation site, it produces a non-N-glycosylated protein, which thereby exhibits a high immunogenicity when, for example, it is allowed to produce, in a eukaryotic cell, an antigen protein derived from a prokaryotic cell.
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Moore Kristi M.
Okuda Takashi
Saito Shuji
Tsuzaki Yoshinari
Armstrong Kratz Quintos Hanson & Brooks, LLP
Housel James C.
Lucas Zachariah
Zeon Corporation
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